treatment of many health problems such as hypertension, diabetes, allergies, cancer,

atherosclerosis, digestive system disorders and inflammation. Inflammatory bowel

diseases are a very serious health problem that significantly reduces a person's quality

of life. Regarding immune-mediated inflammatory diseases, two of the most common

types of inflammatory bowel disease are Crohn's disease (CD) and ulcerative colitis

(UC). Levels of C reactive protein (CRP), neutrophil elastase, leukocyte esterase,

interleukin 1ß (IL-1ß), interleukin receptor 1 antagonist, tumor necrosis factor (TNF),

and eosinophilic cationic protein (ECP) biomarkers observed in the body in

inflammatory bowel diseases. It is reduced by giving the body β-glucan. At the same

time, the percentage of lymphocytes was decreased, and pathways for cytokine and

chemokine marking were developed. This review focuses on the therapeutic effect and

mechanism of β-glucan content derived from fungi, yeasts, and other organic sources

on inflammatory bowel disease (IBD) such as CD and UC, and irritable bowel

syndrome (IBS).